Long-Term Potentiation (LTP) has three properties: (1) input specificity, (2) cooperativity and (3) associativity. In a previous paper, we proposed an integrated model of the mechanisms of the induction and maintenance of LTP with input specificity. In this paper, a model of the mechanism of coopera
THE HIPPOCAMPUS, LONG-TERM POTENTIATION AND MEMORY
โ Scribed by Stephen Redman
- Book ID
- 108936823
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 407 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0305-1870
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Long-Term Potentiation (LTP) in the hippocampus has been considered to be a phenomenon closely related to learning and memory in the brain. In this paper, an integrated model of LTP is constructed based on hypotheses about both the mechanism of LTP induction and that of LTP maintenance, that is, the
We previously found a reduction in the ability of a single 100 Hz ฯซ 1 sec tetanus to induce long-term potentiation (LTP) in the CAl region of hippocampal slices prepared from adult animals. To determine whether this reduction in LTP generation results from changes in neuromodulator function, we exam