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The herbicide ketoclomazone inhibits 1-deoxy-D-xylulose 5-phosphate synthase in the 2-C-methyl-D-erythritol 4-phosphate pathway and shows antibacterial activity against Haemophilus influenzae

✍ Scribed by Matsue, Yukiko; Mizuno, Hiroko; Tomita, Takeo; Asami, Tadao; Nishiyama, Makoto; Kuzuyama, Tomohisa


Book ID
109869113
Publisher
Nature Publishing Group
Year
2010
Tongue
English
Weight
390 KB
Volume
63
Category
Article
ISSN
0021-8820

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Direct formation of 2-C-methyl-d-erythri
✍ Tomohisa Kuzuyama; Shunji Takahashi; Hiroyuki Watanabe; Haruo Seto πŸ“‚ Article πŸ“… 1998 πŸ› Elsevier Science 🌐 French βš– 260 KB

1-Deoxy-D-xyluiose 5-phosphate is biotransformed to 2-C-methyl-D-erythritol 4-phosphate in a single step in the presence of NADPH by a new recombinant enzyme named l-deoxy-D-xylulose 5-phosphate reductoisomerase purified from Escherichia coli.