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Essential Role of Residue H49 for Activity of Escherichia coli 1-Deoxy-d-xylulose 5-Phosphate Synthase, the Enzyme Catalyzing the First Step of the 2-C-Methyl-d-erythritol 4-Phosphate Pathway for Isoprenoid Synthesis

✍ Scribed by Jordi Querol; Manuel Rodrı́guez-Concepción; Albert Boronat; Santiago Imperial

Book ID
115589006
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
265 KB
Volume
289
Category
Article
ISSN
0006-291X

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1-Deoxy-D-xyluiose 5-phosphate is biotransformed to 2-C-methyl-D-erythritol 4-phosphate in a single step in the presence of NADPH by a new recombinant enzyme named l-deoxy-D-xylulose 5-phosphate reductoisomerase purified from Escherichia coli.