✦ LIBER ✦

The Halogenation of 4-Amino-4-deoxy-N 10 -methylpteroylglutamic Acid (Methotrexate) 1 and Other Pteroylglutamic Acid Derivatives 2

✍ Scribed by Angier, Robert B.; Curran, William V.

Book ID: 121419425
Publisher: American Chemical Society
Year: 1959
Tongue: English
Weight: 664 KB
Volume: 81
Category: Article
ISSN: 0002-7863
DOI: 10.1021/ja01520a049

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Metabolite of 4-amino-4-deoxy-N10-methyl

Metabolite of 4-amino-4-deoxy-N10-methylpteroylglutamic acid (methotrexate)

✍ David G. Johns; Ti Li Loo 📂 Article 📅 1967 🏛 John Wiley and Sons 🌐 English ⚖ 417 KB

Amin0-4-deoxy-N'~-methylpteroylglutamic acid (methotrexate; M T X ) is rapidly metabolized by rabbit liver aldehyde oxidase. The MTX metabolite, on oxidative cleavage with permanganate, yields a simple pteridine having the spectrophotometric and chromatographic properties of 2,4-diamino-7-hydroxy-G-

The Synthesis of the 3'-Fluoro and 3',5'

The Synthesis of the 3'-Fluoro and 3',5'-Difluoro Derivatives of 4-Amino-4-deoxy-N 10 -methylpteroylglutamic Acid (Methotrexate) 1

✍ TOMCUFCIK, ANDREW S.; SEEGER, DORIS R. 📂 Article 📅 1961 🏛 American Chemical Society 🌐 English ⚖ 706 KB

The Metabolite of 3',5'-Dichloro-4-amino

The Metabolite of 3',5'-Dichloro-4-amino-4-deoxy-N 10 -methylpteroylglutamic Acid (Dichloromethotrexate)

✍ Li Loo, Ti; Adamson, Richard H. 📂 Article 📅 1965 🏛 American Chemical Society 🌐 English ⚖ 426 KB

Studies on the chemotherapy of leukemia.

Studies on the chemotherapy of leukemia. II. The effect of 4-amino-pteroylglutamic acid and 4-amino-n10-methyl-pteroylglutamic acid on transplanted mouse leukemia

✍ J. H. Burchenal; J. R. Burchenal; M. N. Kushida; S. F. Johnston; B. S. Williams 📂 Article 📅 1949 🏛 John Wiley and Sons 🌐 English ⚖ 381 KB

The 2:1 complex of 4-aminobenzoic acid

The 2:1 complex of 4-aminobenzoic acid and 4,4′-bipyridyl N,N′-dioxide

✍ Moreno-Fuquen, Rodolfo ;Font i Carot, Mercé ;Garriga, Miquel ;Cano, Felix ;Marti 📂 Article 📅 2003 🏛 International Union of Crystallography 🌐 English ⚖ 264 KB

Studies of the metabolism of methotrexat

Studies of the metabolism of methotrexate by intestinal flora—I: Identification and study of biological properties of the metabolite 4-amino-4-deoxy-N10-methylpteroic acid

✍ D.M. Valerino; D.G. Johns; D.S. Zaharko; V.T. Oliverio 📂 Article 📅 1972 🏛 Elsevier Science 🌐 English ⚖ 871 KB