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Studies on the chemotherapy of leukemia. II. The effect of 4-amino-pteroylglutamic acid and 4-amino-n10-methyl-pteroylglutamic acid on transplanted mouse leukemia

✍ Scribed by J. H. Burchenal; J. R. Burchenal; M. N. Kushida; S. F. Johnston; B. S. Williams


Book ID
111697600
Publisher
John Wiley and Sons
Year
1949
Tongue
English
Weight
381 KB
Volume
2
Category
Article
ISSN
0008-543X

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first reported the palliative effects of 4-amino-pteroylglutamic acid in acute leukemia of children. Burchenal and associates2 observed that this compound and its "0-methyl analogue possessed the ability to prolong survival time of mice with a rather acute strain (Ak 4) of transplanted leukemia. The