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The genetics of Familial Alzheimer’s Disease

✍ Scribed by Evelyn A. Devine-Gage; Edmund C. Jenkins; W. Ted Brown; Nikolaos K. Robakis; Henryk M. Wisniewski


Book ID
112749258
Publisher
Springer Netherlands
Year
1988
Tongue
English
Weight
477 KB
Volume
11
Category
Article
ISSN
0161-9152

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## Abstract We performed linkage analysis for age at onset (AAO) in the total Alzheimer's disease (AD) NIMH sample (N = 437 families). Families were subset as late‐onset (320 families, AAO ≥65) and early/mixed (117 families, at least 1 member with 50< AAO <65). Treating AAO as a censored trait, we