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Age-specific incidence rates of Alzheimer's disease in family members participating in the NIA-LOAD genetics study

✍ Scribed by Vardarajan, Badri; Bennett, David; Bird, Thomas; Boeve, Bradley; Farlow, Martin; Foroud, Tatiana; Goate, Alison; Graff-Radford, Neill; Ottman, Ruth; Rosenberg, Roger N.; Schaid, Daniel; Sweet, Robert; Tsuang, Debby; Bennett, J.; Davis, Barb; Faber, Kelley; Garland, Connie; Horner, K.; Kistler, Dana; Kuntz, Karen; Levitch, Denise; Norton, Joanne; Pluff, Lindsay; Reyes, Dolly; Rumbaugh, Malia; Sena, Amanda; Torneten, Sarah; Weamer, Elise; Mayeux, Richard


Book ID
123001215
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
86 KB
Volume
9
Category
Article
ISSN
1552-5260

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## Abstract We performed linkage analysis for age at onset (AAO) in the total Alzheimer's disease (AD) NIMH sample (N = 437 families). Families were subset as late‐onset (320 families, AAO β‰₯65) and early/mixed (117 families, at least 1 member with 50< AAO <65). Treating AAO as a censored trait, we