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The genetic control of alkaline phosphatase activity in the duodenum of the mouse

โœ Scribed by P. R. V. Nayudu; Florence Moog


Publisher
Springer
Year
1967
Tongue
English
Weight
918 KB
Volume
1
Category
Article
ISSN
0006-2928

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There is ample evidence of genetic differences in the level of alkaline phosphatase in blood serum or plasma. Differences have been described between strains of rats (Tuba, '53), and breeds of cattle Kunkel et al., '53; Rusoff et al., '54) and swine (Combs et al., '59). Hypophosphatasia in humans ha

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Quantitative alkaline phosphatase (ALP; EC 3.1.3.1) ## expression varies among various tissues and among inbred mouse strains. There is about a 20-fold difference in ALP activity in lungs from CBA/J and C57L/J inbred strains and this difference is inherited additively with a heritability of 0.84.