The genetic background of ankylosing spo
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Anikó Végvári; Zoltán Szabó; Sándor Szántó; Tibor T. Glant; Katalin Mikecz; Zolt
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Article
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2009
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Elsevier Science
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English
⚖ 177 KB
It has long been known that the major histocompatibility complex (MHC) is essentially involved in genetic susceptibility to ankylosing spondylitis (AS). The HLA-B27 antigen has been accounted for 20 to 50% of the total genetic risk for this disease. However, susceptibility to AS cannot be fully expl