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The genetic background of ankylosing spondylitis

✍ Scribed by Anikó Végvári; Zoltán Szabó; Sándor Szántó; Tibor T. Glant; Katalin Mikecz; Zoltán Szekanecz


Book ID
113684695
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
177 KB
Volume
76
Category
Article
ISSN
1297-319X

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The genetic background of ankylosing spo
✍ Anikó Végvári; Zoltán Szabó; Sándor Szántó; Tibor T. Glant; Katalin Mikecz; Zolt 📂 Article 📅 2009 🏛 Elsevier Science 🌐 English ⚖ 177 KB

It has long been known that the major histocompatibility complex (MHC) is essentially involved in genetic susceptibility to ankylosing spondylitis (AS). The HLA-B27 antigen has been accounted for 20 to 50% of the total genetic risk for this disease. However, susceptibility to AS cannot be fully expl