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Genetics and genomics of ankylosing spondylitis

✍ Scribed by Gethin P. Thomas; Matthew A. Brown

Book ID: 110746685
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 379 KB
Volume: 233
Category: Article
ISSN: 0105-2896
DOI: 10.1111/j.0105-2896.2009.00852.x

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## Abstract ## Objective To define the genetic basis of susceptibility to ankylosing spondylitis (AS), especially non–major histocompatibility complex (MHC) genes. ## Methods The study group comprised 244 affected sibling pairs from 180 pedigrees of primarily European ancestry. Sibling pairs wer