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The gene for multiple endocrine neoplasia type 1: recent findings

✍ Scribed by S.J Marx; S.K Agarwal; C Heppner; Y.S Kim; M.B Kester; P.K Goldsmith; M.C Skarulis; A.M Spiegel; A.L Burns; L.V Debelenko; Z Zhuang; I.A Lubensky; L.A Liotta; M.R Emmert-Buck; S.C Guru; P Manickam; J.S Crabtree; F.S Collins; S.C Chandrasekharappa

Book ID
117808892
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
81 KB
Volume
25
Category
Article
ISSN
8756-3282

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Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1 
✍ Chandrasekharappa, S. C. πŸ“‚ Article πŸ“… 1997 πŸ› American Association for the Advancement of Scienc 🌐 English βš– 458 KB

Multiple endocrine neoplasia–type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by tumors in parathyroids, enteropancreatic endocrine tissues, and the anterior pituitary. DNA sequencing from a previously identified minimal interval on chromosome 11q13 identified several ca