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Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1 

✍ Scribed by Chandrasekharappa, S. C.


Book ID
121157685
Publisher
American Association for the Advancement of Science
Year
1997
Tongue
English
Weight
458 KB
Volume
276
Category
Article
ISSN
0036-8075

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Positional Cloning of the Gene for Multi
✍ Chandrasekharappa, S. C. πŸ“‚ Article πŸ“… 1997 πŸ› American Association for the Advancement of Scienc 🌐 English βš– 458 KB

Multiple endocrine neoplasia–type 1 (MEN1) is an autosomal dominant familial cancer syndrome characterized by tumors in parathyroids, enteropancreatic endocrine tissues, and the anterior pituitary. DNA sequencing from a previously identified minimal interval on chromosome 11q13 identified several ca