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The functional Toll-like receptor 4 Asp299Gly polymorphism is associated with lower left ventricular mass in hypertensive women

✍ Scribed by Maria L. Sales; Roberto Schreiber; Maria C.S. Ferreira-Sae; Maruska N. Fernandes; Cristiane Piveta; José A.A. Cipolli; Antônio Calixto; José R. Matos-Souza; Bruno Geloneze; Kleber G. Franchini; Wilson Nadruz Jr.


Book ID
116348595
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
197 KB
Volume
411
Category
Article
ISSN
0009-8981

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Simple genotype analysis of the Asp299Gl
✍ Naoko Okayama; Kozue Fujimura; Yutaka Suehiro; Yuichiro Hamanaka; Motoki Fujiwar 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 33 KB

## Abstract A nonsynonymous single nucleotide polymorphism (Asp299Gly) in the __Toll‐like receptor‐4__ (__TLR‐4__) gene affects the responsiveness to lipopolysaccharide in humans. To analyze this important polymorphism more efficiently, we developed a simple polymerase chain reaction (PCR) restrict