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Toll-like receptor 4 gene (Asp299Gly) polymorphism associates with carotid artery elasticity: The cardiovascular risk in young Finns study

✍ Scribed by Jussi A. Hernesniemi; Olli T. Raitakari; Mika Kähönen; Markus Juonala; Nina Hutri-Kähönen; Jukka Marniemi; Jorma Viikari; Terho Lehtimäki


Book ID
118421858
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
123 KB
Volume
198
Category
Article
ISSN
0021-9150

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Simple genotype analysis of the Asp299Gl
✍ Naoko Okayama; Kozue Fujimura; Yutaka Suehiro; Yuichiro Hamanaka; Motoki Fujiwar 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 33 KB

## Abstract A nonsynonymous single nucleotide polymorphism (Asp299Gly) in the __Toll‐like receptor‐4__ (__TLR‐4__) gene affects the responsiveness to lipopolysaccharide in humans. To analyze this important polymorphism more efficiently, we developed a simple polymerase chain reaction (PCR) restrict