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Toll-like receptor (TLR) 4 polymorphism Asp299Gly is not associated with disease course in Dutch sarcoidosis patients

✍ Scribed by M. Veltkamp; J. C. Grutters; C. H. M. Van Moorsel; H. J. T. Ruven; J. M. M. Van Den Bosch


Book ID
110090489
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
90 KB
Volume
145
Category
Article
ISSN
0009-9104

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Simple genotype analysis of the Asp299Gl
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## Abstract A nonsynonymous single nucleotide polymorphism (Asp299Gly) in the __Toll‐like receptor‐4__ (__TLR‐4__) gene affects the responsiveness to lipopolysaccharide in humans. To analyze this important polymorphism more efficiently, we developed a simple polymerase chain reaction (PCR) restrict