The first total synthesis of (±)-zenkequinone B
✍ Scribed by Rammohan Devulapally; Yung-Son Hon
- Book ID
- 104099009
- Publisher
- Elsevier Science
- Year
- 2011
- Tongue
- French
- Weight
- 379 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0040-4039
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Brasiliquinone B (2) was synthesized from 7-methoxy-l-tetralone in 8 steps making use of Friedel-Crafts alkylation as a key step.
A general approach to the synthesis of all known strobilurins -a class of natural products -is outlined with strobilurin B as an example. Strobilurin A (1) was first isolated in 1969 under the name of mucidin by Musilek and co-workers 1) from the fungus Oudemansiella mucida. The structure as well a