𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The First Report of Somatic Mutation Reversion X-Linked Chronic Granulomatous Disease

✍ Scribed by Gulbu Uzel; Douglas Kuhns; Gilda Linton; Paul Quie; Steven Holland


Book ID
118616595
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
55 KB
Volume
12
Category
Article
ISSN
1201-9712

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Characterization of 11 novel mutations i
✍ Bénédicte Gérard; Jamel El Benna; Françoise Alcain; Marie-Anne Gougerot-Pocidalo 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 19 KB

The most frequent form of chronic granulomatous disease (CGD) is caused by inactivation of the CYBB gene, which encodes the gp91-phox subunit of phagocyte NADPH oxidase. This defect prevents phagocytes from producing reactive oxygen species and thus from eradicating bacterial and fungal infections.