𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Characterization of 17 new cases of X-linked chronic granulomatous disease with seven novel mutations in the CYBB gene

✍ Scribed by Heiko von Goessel; Johann Peter Hossle; Reinhard Seger; Tayfun Gungor


Book ID
113616104
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
129 KB
Volume
34
Category
Article
ISSN
0301-472X

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Characterization of 11 novel mutations i
✍ BΓ©nΓ©dicte GΓ©rard; Jamel El Benna; FranΓ§oise Alcain; Marie-Anne Gougerot-Pocidalo πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 19 KB

The most frequent form of chronic granulomatous disease (CGD) is caused by inactivation of the CYBB gene, which encodes the gp91-phox subunit of phagocyte NADPH oxidase. This defect prevents phagocytes from producing reactive oxygen species and thus from eradicating bacterial and fungal infections.