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The Expedient Synthesis of 4,2‘-Difluoro-5‘-(7-trifluoromethyl- imidazo[1,2 -a ]pyrimidin-3-yl)biphenyl-2-carbonitrile, a GABA α2/3 Agonist

✍ Scribed by Cameron, Mark; Foster, Bruce S.; Lynch, Joseph E.; Shi, Yao-Jun.; Dolling, Ulf-H.


Book ID
121481491
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
89 KB
Volume
10
Category
Article
ISSN
1083-6160

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✍ Gábor Berecz; József Reiter; Gyula Argay; Alajos Kálmán 📂 Article 📅 2002 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 85 KB

## Abstract **Dedicated to Dr. János Császár on the occasion of his 70^th^ birthday** Ring transformation of 2‐cyanoimido‐3‐methyl‐1,3‐oxazolidine (**10**) yielded 5‐amino‐3‐[__N__‐(2‐hydrox‐yethyl)‐__N__‐methyl]amino‐1__H__‐1,2,4‐triazole (**6**) that was ring closed with different β‐keto esters