The eureka enzyme: the discovery of DNA polymerase
β Scribed by Friedberg, Errol C.
- Book ID
- 109958478
- Publisher
- Nature Publishing Group
- Year
- 2005
- Tongue
- English
- Weight
- 245 KB
- Volume
- 7
- Category
- Article
- ISSN
- 1471-0072
- DOI
- 10.1038/nrm1787
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract **A novel screening approach** based on an oligonucleotideβaddressing enzyme assay enables multiplexed simultaneous profiling of DNA polymerases in nanoliter volumes in terms of their different properties. This approach was used to identify enzymes with altered properties out of a libra
## Abstract DNA polymerase epsilon is a mammalian polymerase that has a tightly associated 3β²β5β² exonuclease activity. Because of this readily detectable exonuclease activity, the enzyme has been regarded as a form of DNA polymerase delta, an enzyme which, together with DNA polymerase alpha, is in