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The Ets transcription factors of the PEA3 group: Transcriptional regulators in metastasis

✍ Scribed by Yvan de Launoit; Jean-Luc Baert; Anne Chotteau-Lelievre; Didier Monte; Laurent Coutte; Sébastien Mauen; Virginie Firlej; Cindy Degerny; Kathye Verreman

Book ID
113486625
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
243 KB
Volume
1766
Category
Article
ISSN
0304-419X

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The PEA3 group of transcription factors belongs to the ets family and is composed of 3 known members, PEA3, ERM and ER81, which are more than 95% identical within the DNAbinding ETS domain and exhibit 50% aa identity overall. Recently, transgenic mice bearing the c-erbB-2/neu oncogene have been show