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THE ENZYMIC CONVERSION OF 1,2,4-TRIAZOLE-3-CARBOXAMIDE TO RIBAVIRIN-5'-PHOSPHATE AND ITS RELATIONSHIP TO THE PROPOSED MECHANISM OF ACTION

โœ Scribed by David G. Streeter; Jon P Miller; Roland K Robins; Lionel N Simon


Book ID
114882875
Publisher
John Wiley and Sons
Year
1977
Tongue
English
Weight
426 KB
Volume
284
Category
Article
ISSN
0890-6564

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Efficient synthesis of 5-fluoroalkylated
โœ Weimin Peng; Shizheng Zhu ๐Ÿ“‚ Article ๐Ÿ“… 2003 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 259 KB

A series of 5-fluoroalkylated 1H-1,2,3-triazoles were synthesized in good yield by the regiospecific 1,3-dipolar cycloaddition reaction of (Z)-ethyl 3-fluoroalkyl-3-pyrrolidino-acrylates with aryl or benzyl azides. In the cases of benzyl azides, addition of Na 2 CO 3 was crucial for a high yield of