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The Enantioselective Organocatalytic 1,4-Addition of Electron-Rich Benzenes to α,β-Unsaturated Aldehydes.

✍ Scribed by Nick A. Paras; David W. C. MacMillan

Publisher
John Wiley and Sons
Year
2010
Weight
39 KB
Volume
33
Category
Article
ISSN
0931-7597

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Organocatalysis [1] has expanded widely within the last few years, since the rediscovery of the proline-catalyzed aldol reaction. [2] Since then, several different methods, such as fluorination, [3] chlorination, [4] bromination, [5] sulfenylation, [6] amination, [7] and Mannich reactions, [8] have