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Formal Highly Enantioselective Organocatalytic Addition of Fluoromethyl Anion to α,β-Unsaturated Aldehydes

✍ Scribed by Andrea-Nekane Alba; Xavier Companyó; Albert Moyano; Ramon Rios


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
235 KB
Volume
15
Category
Article
ISSN
0947-6539

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Organocatalysis [1] has expanded widely within the last few years, since the rediscovery of the proline-catalyzed aldol reaction. [2] Since then, several different methods, such as fluorination, [3] chlorination, [4] bromination, [5] sulfenylation, [6] amination, [7] and Mannich reactions, [8] have