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The effects of prefrontal intracortical microinjections of an alpha-2 agonist, alpha-2 antagonist and lidocaine on the delayed alternation performance of aged rats

✍ Scribed by Heikki Tanila; Pia Rämä; Synnöve Carlson

Book ID
118408002
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
345 KB
Volume
40
Category
Article
ISSN
0361-9230

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The effects of prefrontal intracortical
The effects of prefrontal intracortical microinjections of an alpha-2 agonist, alpha-2 antagonist and lidocaine on the delayed alternation performance of aged rats
✍ Heikki Tanila; Pia Rämä; Synnöve Carlson 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 345 KB

A selective alpha-2 agonist medetomidine, a selective alpha-2 antagonist atipamezole and lidocaine were injected into the prefrontal cortex of aged rats that had been trained to perform a delayed alternation (DA) task in a T maze. Medetomidine at the dose of 0.01 /zg//zl improved the memory task per