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The effects of atipamezole, an Alpha-2 antagonist, on the performance of young and aged rats in the delayed nonmatching to position task

✍ Scribed by Jouni Sirviö; Keijo Lukkarinen; Paavo Riekkinen Jr.; Esa Koivisto; Raimo Virtanen; Arto Pennanen; Antti Valjakka; Paavo J. Riekkinen

Book ID
113224239
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
500 KB
Volume
39
Category
Article
ISSN
0091-3057

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✍ Heikki Tanila; Pia Rämä; Synnöve Carlson 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 345 KB

A selective alpha-2 agonist medetomidine, a selective alpha-2 antagonist atipamezole and lidocaine were injected into the prefrontal cortex of aged rats that had been trained to perform a delayed alternation (DA) task in a T maze. Medetomidine at the dose of 0.01 /zg//zl improved the memory task per