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The effects of p21-N-ras expression in NIH-3T3 cells upon cyclic AMP metabolism

✍ Scribed by Shireen-A. Davies; Miles D. Houslay; Michael J.O. Wakelam


Book ID
119120889
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
689 KB
Volume
1013
Category
Article
ISSN
0167-4889

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Examination of the effect of the farnesylprotein transferase (FPTase) inhibitor UCF1-C/manumycin on NIH3T3 cells transfected with a normal N-ras gene and expressing high levels of the corresponding p21-ras protein showed that 10 m UCF1-C immediately and reversibly inhibited growth in these cells, wi