๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

The effects of cimetidine upon the plasma pharmacokinetics of doxorubicin in rabbits

โœ Scribed by Dean E. Brenner; Jerry C. Collins; Kenneth R. Hande

Publisher
Springer
Year
1986
Tongue
English
Weight
438 KB
Volume
18
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.

๐Ÿ“œ SIMILAR VOLUMES

Effect of phenytoin on the pharmacokinet
Effect of phenytoin on the pharmacokinetics of doxorubicin and doxorubicinol in the rabbit
โœ Barry J. Cusack; Dwaine A. Tesnohlidek; Vicki L. Loseke; Robert E. Vestal; Dean ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 541 KB

Doxorubicin is metabolized extensively to doxorubicinol by the ubiquitous aldoketoreductase enzymes. The extent of conversion to this alcohol metabolite is important since doxorubicinol may be the major contributor to cardiotoxicity. Aldoketoreductases are inhibited in vitro by phenytoin. The presen

The influence of ranitidine on the pharm
The influence of ranitidine on the pharmacokinetics and toxicity of doxorubicin in rabbits
โœ N. Lindsay Harris; Dean E. Brenner; Lowell B. Anthony; Jerry C. Collins; Susan H ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 596 KB

The influence of ranitidine on the pharmacokinetics and toxicity of doxorubicin was studied in six female New Zealand white rabbits. Plasma pharmacokinetic data were first obtained from rabbits given 3 mg/kg doxorubicin. After 1 month, the same rabbits were treated with ranitidine, 2.5 mg/kg or 25 m