๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Effect of a low-protein diet on doxorubicin pharmacokinetics in the rabbit

โœ Scribed by Barry J. Cusack; Stephan P. Young; Vicki L. Loseke; Michelle R. Hurty; Loring Beals; Richard D. Olson


Publisher
Springer
Year
1992
Tongue
English
Weight
485 KB
Volume
30
Category
Article
ISSN
0344-5704

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Effect of phenytoin on the pharmacokinet
โœ Barry J. Cusack; Dwaine A. Tesnohlidek; Vicki L. Loseke; Robert E. Vestal; Dean ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 541 KB

Doxorubicin is metabolized extensively to doxorubicinol by the ubiquitous aldoketoreductase enzymes. The extent of conversion to this alcohol metabolite is important since doxorubicinol may be the major contributor to cardiotoxicity. Aldoketoreductases are inhibited in vitro by phenytoin. The presen

The influence of ranitidine on the pharm
โœ N. Lindsay Harris; Dean E. Brenner; Lowell B. Anthony; Jerry C. Collins; Susan H ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› Springer ๐ŸŒ English โš– 596 KB

The influence of ranitidine on the pharmacokinetics and toxicity of doxorubicin was studied in six female New Zealand white rabbits. Plasma pharmacokinetic data were first obtained from rabbits given 3 mg/kg doxorubicin. After 1 month, the same rabbits were treated with ranitidine, 2.5 mg/kg or 25 m

Effect of indomethacin on the pharmacoki
โœ Tawfeeg A. O. Najjar; Abdel Rehim M. Morad; Rao Muzaffar A. Khan ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 300 KB ๐Ÿ‘ 3 views

## Abstract The interaction between indomethacin (IND) and methotrexate (MTX) was investigated in rabbits. The study was designed so as to evaluate the effect of IND (1 mg h^โˆ’1^) during a continuous MTX infusion (1ยท2 mg kg^โˆ’1^) over 240 min. IND was injected i.v. at hourly intervals after a steady