𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effect of cimetidine on the pharmacokinetics of quinidine and lidocaine in the rat

✍ Scribed by Richard J. Fruncillo; G. John DiGregorio; Adam Soll


Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
350 KB
Volume
72
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Influence of quinidine, cimetidine, and
✍ Vanessa Bergamin Boralli; Eduardo Barbosa Coelho; Vera Lucia Lanchote πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 252 KB πŸ‘ 1 views

## Abstract Metoprolol is a β‐blocker and its racemic mixture is used for the treatment of hypertension. In the present study we investigated the influence of CYP2D and CYP3A on the stereoselective metabolism of metoprolol in rats. Male Wistar rats (__n__ = 6 per group) received racemic metoprolol

Effect of cimetidine on quinidine bioava
✍ Janis J. Mackichan; Harisios Boudoulas; Stephen F. Schaal πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 280 KB πŸ‘ 2 views

Elevations in quinidine steady-state serum concentrations have been re orted in patients who received cimetidine concurrently."' Studies in normal volunteers3' have shown that areas under the serum concentration-time curve of orally administered quinidine are higher when quinidine is given during ch

The effect of hypoxic hypoxia on the sys
✍ Yi Fei Huang; Richard N. Upton πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 132 KB

It was hypothesized that the increased myocardial blood flow known to occur during some types of hypoxia may alter the kinetics and dynamics of cardio-active drugs such as lidocaine that act directly on the myocardium. In a randomized cross-over design, iv lidocaine (100 mg over 2 min) was administe

Effect of bupropion on cimetidine and ra
✍ Musbah O. M. Tanira; Juzar S. Kaka; Khalil I. Al-Khamis πŸ“‚ Article πŸ“… 1989 πŸ› John Wiley and Sons 🌐 English βš– 329 KB πŸ‘ 2 views

Cimetidine and ranitidine absorption were studied in rats, alone or in combination with concurrent but separate bupropion oral admininstration. Blood samples were collected before and 0.25, 0.5, 0.75, 1.0, 1-5, 2.0, 3.0, 4.5, and 6.0 h after dosing. In ranitidinetreated rats, an exta blood sample at

No effect of chloroquine on theophylline
✍ Bedassa A. Motti; Michael Ashton πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 120 KB πŸ‘ 2 views

The immediate and delayed effects of chloroquine on theophylline kinetics were investigated in rats pretreated with chloroquine diphosphate (45 mg kg -1 ) or saline intraperitoneally. One hour or 4 days after chloroquine, theophylline (10 mg kg -1 ) was administered intravenously. Compared with the