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The effector interactions of p21ras

✍ Scribed by Marshall, Mark S.


Book ID
123045112
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
520 KB
Volume
18
Category
Article
ISSN
0968-0004

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ras proteins are positively regulated by nucleotide exchange factors and negatively regulated by GTPaseactivating proteins (GAPs). Two GAPs have been found in mammalian cells, pl2OGAP and neurofibromin, the product of the type 1 neurofibromatosis (NF7) gene. A library of substitutions in the effecto