## Abstract Gastric emptying of isotopically labelled solid meals was studied in normal human subjects and in 30 patients who had had an operation for chronic duodenal ulcer. Each patient had a vagotomy of the whole stomach combined with either a Finney pyloroplasty to produce a large gastric outle
The effect of vagotomy and drainage operations on the rate of gastric emptying in duodenal ulcer patients
β Scribed by W. T. Davies; G. H. Griffith; G. M. Owen; Professor R. Shields
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 518 KB
- Volume
- 61
- Category
- Article
- ISSN
- 0007-1323
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β¦ Synopsis
Abstract
The rate of gastric emptying was estimated in 29 patients with duodenal ulcers, before and after vagotomy and drainage operations, by measuring the disappearance from the stomach of a standard meal containing radioactive chromium. When Heineke-Mikulicz pyloroplasty accompanied vagotomy gastric emptying was observed to be slowed, whereas after vagotomy and Fitmey pyloroplasty the rate of gastric emptying was more rapid when compared with the preoperative rate. Gastric emptying after vagotomy and gastrojejunostomy showed no consistent alteration in rate. Temporary gastric stasis occurred in the early postoperative period after vagotomy and drainage procedures.
π SIMILAR VOLUMES
## Summary A proximal gastric vagotomy (PGV) prevented experimental duodenal ulcers in rats for only 5 days and thereafter all rats developed duodenal ulceration. In sham-operated rats the mean stimulated gastric acid output was 186 ΞΌmol/60 min. Immediately following a PGV there was a significant d
## Abstract A consecutive series of 25 patients with chronic duodenal ulcer has been treated by highly selective vagotomy without a drainage procedure. The vagal fibres passing to the distal 5β7 cm. of the stomachβthe nerves of Latarjetβwere left intact, as were the hepatic and coeliac branches of