## Summary A proximal gastric vagotomy (PGV) prevented experimental duodenal ulcers in rats for only 5 days and thereafter all rats developed duodenal ulceration. In sham-operated rats the mean stimulated gastric acid output was 186 ฮผmol/60 min. Immediately following a PGV there was a significant d
The effect of the size of the gastric outlet on gastric emptying after vagotomy for duodenal ulcer
โ Scribed by W. D. George; D. J. Cowley; C. M. Royston; H. I. Glass; J. Spencer
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 297 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0007-1323
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โฆ Synopsis
Abstract
Gastric emptying of isotopically labelled solid meals was studied in normal human subjects and in 30 patients who had had an operation for chronic duodenal ulcer. Each patient had a vagotomy of the whole stomach combined with either a Finney pyloroplasty to produce a large gastric outlet or a Heineke-Mikulicz pyloroplasty to produce a relatively small outlet.
At 10โ22 days after operation gastric emptying was equally and significantly slowed in both groups when compared with the normal controls. This delay occurred regardless of whether the vagotomy was complete or incomplete.
At 4โ6 months after operation emptying had returned to normal in the patients who had had a Finney pyloroplasty but remained significantly slowed after Heineke-Mikulicz pyloroplasty.
Mild symptoms of gastric stasis frequently occurred in both groups in the early postoperative period, but were rare 4โ6 months after operation. There was no correlation between the incidence of these early symptoms of stasis and the size of the gastric outlet constructed.
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