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The effect of tobacco smoke, nicotine, and cotinine on the mutagenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)

✍ Scribed by Buddy Brown; Jerry Avalos; Chin Lee; David Doolittle


Book ID
117766723
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
123 KB
Volume
494
Category
Article
ISSN
1383-5718

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## Abstract Urinary metabolites of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) and its glucuronides, termed total NNAL, have recently been shown to be good predictors of lung cancer risk, years before di