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The effect of nimesulid (a selective COX-2 blocker) on IL1-beta protein expression in human endometrial cells in culture

✍ Scribed by Erkut Attar

Book ID: 119419671
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 19 KB
Volume: 78
Category: Article
ISSN: 1556-5653
DOI: 10.1016/s0015-0282(02)04068-2

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## Abstract ## Background. The protooncogenes Ets‐1 and Ets‐2 are involved in carcinogenesis of different tumors. Nimesulide, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has antiproliferative effects on tumor cells. The question arises whether nimesulide influences Ets‐1 and Ets‐2 synthesis in