## Abstract Our previous study showed that aspirin induced apoptosis of esophageal cancer cells __in vitro__ by inhibiting the pathway of NF‐kappaB downstream regulation of cyclooxygenase‐2. The purpose of this study was to determine if similar changes occurred __in vivo__ in the tumors of patients
The effect of COX-2 inhibitor, nimesulide, on angiogenetic factors in primary endometrial carcinoma cell culture
✍ Scribed by S. Genç; E. Attar; F. Gürdöl; S. Kendigelen; A. Bilir; H. Serdaroğlu
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 115 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0372-8722
No coin nor oath required. For personal study only.
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## Abstract ## Background. The protooncogenes Ets‐1 and Ets‐2 are involved in carcinogenesis of different tumors. Nimesulide, a selective cyclooxygenase‐2 (COX‐2) inhibitor, has antiproliferative effects on tumor cells. The question arises whether nimesulide influences Ets‐1 and Ets‐2 synthesis in
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