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Effects of the dual 5 α-reductase inhibitor dutasteride on apoptosis in primary cultures of prostate cancer epithelial cells and cell lines

✍ Scribed by Ann Maria McCrohan; Colm Morrissey; Conor O'Keane; Niall Mulligan; Chanel Watson; James Smith; John M. Fitzpatrick; R. William G. Watson


Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
241 KB
Volume
106
Category
Article
ISSN
0008-543X

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✍ Takuya Kanazawa; Jumpei Enami; Kaoru Kohmoto 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 200 KB

We examined the effects of 1alpha,25-dihydroxycholecalciferol (1,25-DHCC) and the glucocorticoid, cortisol, on primary mouse mammary epithelial cells in collagen gel cell culture systems. Physiological low concentrations (10(-11)-10(-9) M) of 1,25-DHCC stimulated growth of the cells in a collagen ge