Effects of small molecule inhibitors of
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Lova Segerström; Ninib Baryawno; Baldur Sveinbjörnsson; Malin Wickström; Lotta E
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Article
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2011
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John Wiley and Sons
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French
⚖ 691 KB
## Abstract Activation of the PI3K/Akt signaling pathway is correlated with poor prognosis in neuroblastoma, the most common and deadly extracranial tumor of childhood. In this study, we show that the small‐molecule inhibitors of phosphoinositide‐dependent protein kinase‐1 (PDK1) OSU03012 and the d