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189 Antitumor Effect of the MTor Inhibitor Everolimus in Combination with Trastuzumab On Human Breast Cancer Stem Cells in Vitro and in Vivo

✍ Scribed by J. Zhang; X. Zhang; S. Zhang; Y. Liu; Y. Ma; J. Liu


Book ID
117662100
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
57 KB
Volume
48
Category
Article
ISSN
0959-8049

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## Abstract Mammalian target of rapamycin (mTOR) is considered to be a major effector of cell growth and proliferation that controls protein synthesis through a large number of downstream targets. We investigated the expression of the phosphatidylinositol 3′‐kinase (PI3K)/mTOR signaling pathway in