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The effect of hyperthermia on the uptake and cytotoxicity of melphalan in chinese hamster ovary cells

โœ Scribed by Diana A. Bates; William J. Mackillop

Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
564 KB
Volume
16
Category
Article
ISSN
0360-3016

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A strong teratogen-6-aminonicotinamide (6-AN)-was tested for its ability to induce cytotoxicity and mutagenicity in Chinese hamster ovary (CHO) cells. Tests were performed in the presence and absence of a metabolic activation system (S-9 mix). Cytotoxicity was evaluated in CHO cells by the total pro