A strong teratogen-6-aminonicotinamide (6-AN)-was tested for its ability to induce cytotoxicity and mutagenicity in Chinese hamster ovary (CHO) cells. Tests were performed in the presence and absence of a metabolic activation system (S-9 mix). Cytotoxicity was evaluated in CHO cells by the total pro
Differential cytotoxicity of sodium arsenite in human fibroblasts and Chinese hamster ovary cells
β Scribed by Te-Chang Lee; Jiunn-Liang Ko; K.Y. Jan
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 673 KB
- Volume
- 56
- Category
- Article
- ISSN
- 0300-483X
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Arsenic is the first metal to be identified as a human carcinogen. Arsenite, one inorganic form of arsenic, has been found to induce sister chromatid exchange, chromosome aberrations, and gene amplification in a variety of in vitro systems. In this study of arsenite-induced genotoxicity represented
Stability of heterologous protein expression during production is critical for regulatory approval of vaccine and therapeutic products. Leishmania GP63, a zinc metalloproteinase that is a potential vaccine candidate, has been expressed on the surface of Chinese hamster ovary (CHO) cells. Flow cytome