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The effect of folic acid supplementation on the toxicity of low-dose methotrexate in patients with rheumatoid arthritis

✍ Scribed by Sarah L. Morgan; Joseph E. Baggott; William H. Vaughn; Peggy K. Young; Janet V. Austin; Carlos L. Krumdieck; Graciela S. Alarcon


Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
872 KB
Volume
33
Category
Article
ISSN
0004-3591

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πŸ“œ SIMILAR VOLUMES


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✍ D. Oguey; F. KΓΆlliker; N. J. Gerber; J. Reichen πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 355 KB πŸ‘ 2 views

Objective. To evaluate the influence of food on the bioavailability of an oral dose of methotrexate in patients with rheumatoid arthritis. Methods. Methotrexate (15 mg) was given intravenously and orally, with or without a meal, to 10 patients. Blood samples were drawn at specific intervals to eval

The effect of folic acid and folinic aci
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## Abstract ## Objective To determine if folinic acid supplementation during methotrexate (MTX) therapy for rheumatoid arthritis (RA) reduces both urinary 5‐aminoimidazole‐4‐carboxamide (AICA) and urinary adenosine excretion more than does folic acid supplementation. AICA and adenosine are markers