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THE EFFECT OF DEHYDRATION ON THE SEIZURE THRESHOLD AND ELECTROLYTE CONTENT OF BRAIN IN RATS

✍ Scribed by P. SILBERSTEIN

Book ID
118704687
Publisher
John Wiley and Sons
Year
1967
Tongue
English
Weight
318 KB
Volume
3
Category
Article
ISSN
1034-4810

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The effect of inhibiting endogenous brain thromboxane (TXB2) on pentylenetetrazole-induced seizures was studied using the thromboxane synthetase inhibitors OKY-1581 (20 mgikg) and UK 38,485 (50 mgikg). Both compounds selectively decreased ( > 90%) TXB2 production in brain measured after 2 min of con