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Effect of aminophylline on seizure thresholds and brain regional cyclic nucleotides in the rat

โœ Scribed by Jonathan E. Walker

Book ID
115897282
Publisher
Elsevier Science
Year
1981
Tongue
English
Weight
348 KB
Volume
74
Category
Article
ISSN
0014-4886

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## Abstract Convulsant doses of pentylenetetrazol (100 mg/kg) increase levels of both cyclic adenosine monophosphate (AMP) and cyclic guanosine monophosphate (GMP) in mouse cerebral cortex and hippocampus. In animals pretreated with reserpine, propranolol, or aminophylline, pentylenetetrazol seizur