The effect of cholesterol on the optical properties of lecithin bilayers
β Scribed by R.J. Cherry; D.E. Graham; D. Chapman
- Publisher
- Elsevier Science
- Year
- 1971
- Tongue
- English
- Weight
- 250 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0009-3084
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β¦ Synopsis
Measurements have been made of the optical reflectance of egg lecithin-cholesterol bilayers and a value of 64 Β± 4 ,~ obtained for the bilayer thickness. There is some evidence that Ca ++ binds to the bilayer when the ion concentration in the aqueous phase is greater than 2M. These results are compared with those obtained for egg lecithin bilayers in the absence of cholesterol.
π SIMILAR VOLUMES
Current evidence strongly suggests that a substantial fraction of the phospholipids in many membranes are arranged into fluid bilayers (1). Although the word "bilayer" is self-explanatory, the term "fluid" is not. This paper summarizes recent data on the fatty acid configurations, dynamics, and conf
Paramagnetic resonance of cholestane and three fatty acid probes is used to measure the effects of the addition of cholesterol, 7-dehydrocholesterol and ergosterol to egg phosphatidylcholine bilayers. At low concentrations we find that all three sterols effectively align the bilayers. However, conce
The temperature dependence of the area-specific conductance of egg-lecithin/cholesterol bilayers formed with n-hexadecane in 1 mM KCI has been studied. From Arrhenius plots the activation energy for conduction was measured as 35 -+ 2 kJ/mol. Comparison of this value with those predicted by various m