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The effect of cations on the asymmetric conjugate addition of organocopper reagents to chiral vinyl sulfoximines

✍ Scribed by Stephen G. Pyne

Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
245 KB
Volume
27
Category
Article
ISSN
0040-4039

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✦ Synopsis

The chiral vinyl sulfsximines lb and q have been prepared. The effect of cations -(Li+, Zn'+) on the stereochemical outcome of their conjugate addition reactions with organocopper reagents is reported.

Recently we reported that chiral vinyl sulfoximines la underwent conjugate addition reactions with dialkylcopper lithium reagents (R2CuLi. LiI) to yield a mixture of two

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