The goal of the study was to evaluate the impact of amorphous bulking agents on the chemical stability of freeze-dried materials. Polyvinylpyrrolidone and dextran of different molecular weights and lactose were used as bulking agents, and sucrose was used as an example of an acid-sensitive compound.
The Effect of Bulking Agent on the Solid-State Stability of Freeze-Dried Methylprednisolone Sodium Succinate
β Scribed by Beth D. Herman; Brent D. Sinclair; Nathaniel Milton; Steven L. Nail
- Book ID
- 110379343
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Weight
- 948 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0724-8741
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