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The Effect of Breakfast on the Oral Bioavailability of Tacrolimus in Diabetic and Nondiabetic Patients Before Transplantation

✍ Scribed by E van Duijnhoven; M Christiaans; N Undre; P Stevenson; J van Hooff


Book ID
117236086
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
183 KB
Volume
30
Category
Article
ISSN
0041-1345

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The enhancing effects of cyclodextrins (CyDs) on the solubility, the dissolution rate, and the bioavailability of tacrolimus after oral administration to rats were examined and compared with those after administration of a PROGRAF 1 capsule containing the solid dispersion formulation of tacrolimus.