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The effect of a yeast extract (PCO) on the mitotic activity of neoplastic and normal cells in vitro

✍ Scribed by John C. Fardon; Sister M. Eymard Poydock; Yoshiki Tsuchiya


Publisher
John Wiley and Sons
Year
1973
Tongue
English
Weight
284 KB
Volume
5
Category
Article
ISSN
0022-4790

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✦ Synopsis


Abstract

An aqueous‐alcoholic extract of yeast (PCO) was found to inhibit mitoses in Sarcoma 180, Krebs‐2 ascites carcinoma, and the L–1210 leukemia in vitro. Contrariwise, PCO did not inhibit, and in some experiments even stimulated, the mitoses in the following normal cells in vitro: L‐929 fibroblasts; two established lines of mouse corneal cells; and mouse bone marrow cells.


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