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The effect of 2-macroglobulin on VEGF-induced endothelin-1 upregulation in human umbilical vein endothelial cells

โœ Scribed by Min-Jeong Oh; Jung-Ho Shin; Sang-Hee Chung; Hyun-Joo Seol; Hai-Joong Kim

Book ID
113430018
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
59 KB
Volume
193
Category
Article
ISSN
1097-6868

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EFFECT OF FGF-1 AND FGF-2 ON VEGF BINDIN
EFFECT OF FGF-1 AND FGF-2 ON VEGF BINDING TO HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS
โœ Jun-Hui Chen; Xin-Chang Wang; Mikio Kan; J.Denry Sato ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 89 KB

When FGF-1 or FGF-2 and VEGF were added together, the mitogenic effect of FGF-1 or FGF-2 and VEGF on HUVEC was additive. However, when HUVECs were preincubated for 2 days with 10 ng/ml FGF-1 in the absence of VEGF, the Scatchard plot of [125I]VEGF binding sites was shifted to the right: both affinit